Job Summary
Lead the creation and synthesis of nucleoside-based molecules and conjugates designed to enhance intracellular delivery and endosomal escape. Partner with cross-functional colleagues to progress oligonucleotide therapeutics from early discovery into lead optimization.
Responsibilities
- Guide the design and synthesis of nucleoside-based compounds and conjugates that support intracellular delivery and endosomal escape.
- Work with cross-functional teams to advance oligonucleotide therapeutic programs from early-stage discovery through lead optimization.
Qualifications
- PhD in Medicinal Chemistry, Synthetic Organic Chemistry, Chemical Biology, or a related discipline.
- At least 5 years of experience in nucleoside chemistry.
- Demonstrated expertise in multistep organic synthesis.
The businesses of Merck KGaA, Darmstadt, Germany provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.
